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Título: | Label-free DNA biosensors based on functionalized carbon nanotube field effect transistors |
Autor: | Martínez Fernández de Landa, María Teresa CSIC ORCID ; Tseng, Yu-Chih; Ormategui, Nerea; Loinaz, Iraida; Eritja Casadellà, Ramón CSIC ORCID ; Bokor, Jeffrey | Fecha de publicación: | 2009 | Editor: | American Chemical Society | Citación: | Nano Letters 9(2): 530-536 (2009) | Resumen: | A carbon nanotube transistor array was used to detect DNA hybridization. A new approach to ensure specific adsorption of DNA to the nanotubes was developed. The polymer poly (methylmethacrylate0.6-co-poly(ethyleneglycol)methacrylate0.15-co-N-succinimidyl methacrylate0.25) was synthesized and bonded noncovalently to the nanotube. Aminated single-strand DNA was then attached covalently to the polymer. After hybridization, statistically significant changes were observed in key transistor parameters. Hybridized DNA traps both electrons and holes, possibly caused by the charge-trapping nature of the base pairs. | Versión del editor: | https://doi.org/10.1021/nl8025604 | URI: | http://hdl.handle.net/10261/255380 | DOI: | 10.1021/nl8025604 | ISSN: | 1530-6984 |
Aparece en las colecciones: | (ICB) Artículos |
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