Functional epigenetics and epitranscriptomics and their role in health and disease

Abstract

In recent years, there have been great efforts to characterize the epigenome and epitranscriptome of different cell types and organisms. However, most of those studies are descriptive and we still ignore the role of many epi-modifications. We discuss the need of gaining functional and mechanistic insight and the large impact that this knowledge will have in the understanding and treatment of numerous diseases.