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Título: | BRAIN & SPINAL CORD DAMAGE & REHABILITATION |
Autor: | Álvarez-Dolado, Manuel CSIC ORCID CVN; Casas-Tinto, Sergio CSIC ORCID; Corbí, Angel L. ; De Las Rivas, Javier CSIC ORCID CVN ; Delgado, Manuel; Fuentes-García, Manuel; González-Rey, Elena CSIC ORCID; Iglesias, Teresa CSIC ORCID; Llebaria, Amadeu CSIC ORCID; López-Atalaya, José P. CSIC ORCID; Mittelbrunn, María CSIC ORCID CVN; Rocón, Eduardo CSIC ORCID; Serrano, Teresa; Villa, Rosa CSIC ORCID ; Yúfera, Alberto CSIC ORCID; Duarte, Esther; Gil-Agudo, Ángel; Planas, Anna M. CSIC ORCID; Moreno, Juan Camilo CSIC ORCID | Palabras clave: | troke traumatic brain injurybiomarkers for CNS injury neuroplasticityneural repair neural regenerationneurorehabilitation technologyneuroinflammation neuroprotection | Fecha de publicación: | 2021 | Editor: | Consejo Superior de Investigaciones Científicas (España) | Citación: | White Paper 5: Brain, Mind and Behaviour: 107- 123 (2021) | Resumen: | Stroke and traumatic injury in brain or spinal cord are often life-threating conditions and major causes of death or permanent disability with high impact in the health care system. There are several stages of intervention to improve the neurological outcome. Acutely, fast interventions aiming to reestablish cerebral blood flow in ischemic stroke, to stop bleeding after brain hemorrhage, and to reduce edema after contusions are amongst mandatory actions. Current studies aim to develop accompanying strategies for brain cell protection based on enhancing endogenous protective mechanism, blocking cell death pathways, or through immunomodulation. After the acute phase, interventions are intended to promote recovery of function using rehabilitation with state-of-the-art technologies enabled by robotics. Other advanced strategies include cell, gene, and immune therapies, and brain function modulation with the aid of smart nanotechnologies. There is great expectation in the fast evolving novel approaches for improvement of neurological deficits in these unpredictable and devastating condition | URI: | http://hdl.handle.net/10261/250598 | Identificadores: | isbn: Vol. 5: 978-84-00-10746-8 |
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