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Aging and Brain Deterioration

AuthorsBoya, Patricia CSIC ORCID ; Torres Alemán, Ignacio CSIC ORCID; Sanfeliu, Coral CSIC ORCID; Varela-Nieto, Isabel CSIC ORCID ; Ávila, Jesús CSIC ORCID ; Carrión-Vázquez, Mariano Sixto CSIC ORCID; Peral, Belén CSIC ORCID; Pascual-Teresa, Sonia de CSIC ORCID ; Nova, Esther CSIC ORCID ; Rojo Pérez, Fermina CSIC ORCID CVN ; Fernández-Mayoralas, Gloria CSIC ORCID ; Moreno Fuentes, Francisco Javier CSIC ORCID ; Sánchez-Mut, José Vicente CSIC ORCID; Araque, Alfonso CSIC ORCID; Sánchez González, Diego; Ballesteros Jiménez, Soledad; Hernández Pérez, Félix CSIC ORCID; Dotti, Carlos G. CSIC ORCID; Rodríguez Rodríguez, Vicente CSIC ORCID
Issue Date2021
PublisherEditorial CSIC
CitationBrain, Mind and Behaviour 5(7): 96-105 (2021)
AbstractAdvanced age significantly increases the risk of developing chronic diseases such as cancer, diabetes, cardiovascular, immune and mental disease. Regarding the latter, advanced age is a necessary factor for the development of non-hereditary forms of neurodegenerative diseases such as Alzheimer’s and Parkinson’s. Despite years of intense research, we still do not know how these diseases occur, this being one of the main reasons for the lack of adequate interventions to prevent or cure these pathologies. To overcome the current limitations in the field, we plan to: 1) generate basic knowledge on the mechanisms responsible for cognitive, behavioral, motor, metabolic and sociability disorders that occur with age, 2) define the mechanisms that determine individual susceptibility to neurodegeneration, 3) design and develop strategies to improve brain aging, and 4) explore social and environmental conditions of the older population to know their influence in brain degeneration. Individual, social and policy interventions must be considered for future research.
DescriptionCarlos Dotti and Vicente Rodríguez (coordinators).
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