English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/24347
Compartir / Impacto:
Estadísticas
Add this article to your Mendeley library MendeleyBASE
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Título

Cyclic AMP can decrease expression of genes subject to catabolite repression in Saccharomyces cerevisiae

AutorZaragoza, Oscar; Lindley, Chris; Gancedo, Juana M.
Fecha de publicaciónabr-1999
EditorAmerican Society for Microbiology
CitaciónJournal of Virology 181(8): 2640-2642 (1999)
ResumenExternal cyclic AMP (cAMP) hindered the derepression of gluconeogenic enzymes in a pde2 mutant ofSaccharomyces cerevisiae, but it did not prevent invertase derepression. cAMP reduced nearly 20-fold the transcription driven by upstream activation sequence (UAS1FBP1) from FBP1, encoding fructose-1,6-bisphosphatase; it decreased 2-fold the activation of transcription by UAS2FBP1. Nuclear extracts from cells derepressed in the presence of cAMP were impaired in the formation of specific UASFBP1-protein complexes in band shift experiments. cAMP does not appear to act through the repressing protein Mig1. Control of FBP1 transcription through cAMP is redundant with other regulatory mechanisms.
Descripción3 pages, 2 figures, 2 table.
Versión del editorhttp://jb.asm.org/cgi/content/short/181/8/2640
URIhttp://hdl.handle.net/10261/24347
ISSN1098-5530
Aparece en las colecciones: (IIBM) Artículos
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
2640.pdf276,52 kBAdobe PDFVista previa
Visualizar/Abrir
Mostrar el registro completo
 


NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.