English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/24117
Compartir / Impacto:
Estadísticas
Add this article to your Mendeley library MendeleyBASE
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Título

Catabolite inactivation of the yeast maltose transporter occurs in the vacuole after internalization by endocytosis

AutorRiballo, Enriqueta; Herweijer, Marga; Wolf, Dieter H.; Lagunas, Rosario
Fecha de publicaciónoct-1995
EditorAmerican Society for Microbiology
CitaciónJournal of Bacteriology 177(19): 5622-5627 (1995)
ResumenThe maltose transporter of Saccharomyces cerevisiae is rapidly degraded during fermentation in the absence of a nitrogen source. The location and mechanism of degradation of the transporter have been investigated. Using mutants defective in endocytosis, we have shown that degradation of this transporter requires internalization by endocytosis. In addition, studies of mutants defective in proteasome or vacuolar proteolysis revealed that degradation occurs in the vacuole and is independent of proteasome function. The results also revealed that degradation of the maltose transporter requires Sec18p and raised the question of whether in the absence of Sec18p activity the internalized maltose transporter is recycled back to the plasma membrane.
Descripción6 pages, 5 figures, 2 tables.
Versión del editorhttp://jb.asm.org/cgi/content/short/177/19/5622
URIhttp://hdl.handle.net/10261/24117
ISSN0021-9193
Aparece en las colecciones: (IIBM) Artículos
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
5622.pdf326,37 kBAdobe PDFVista previa
Visualizar/Abrir
Mostrar el registro completo
 


NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.