English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/234047
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE
Exportar a otros formatos:


Photosensitised biphotonic chemistry of pyrimidine derivatives

AuthorsAlzueta, O.R.; Cadet, J.; Cuquerella, M.Consuelo; Miranda, M. A.
Issue Date10-Mar-2020
PublisherRoyal Society of Chemistry (UK)
CitationOrganic and Biomolecular Chemistry 18(12): 2227-2232 (2020)
AbstractPhotosensitised biphotonic irradiation of DNA has been rarely addressed, probably due to the difficulties in the experimental design. This is associated with the selection of nucleobases and sensitisers with appropriate absorption spectra and photochemical reactivity, in combination with a laser source emitting intense UVA light of the adequate wavelength. The present paper presents a new strategy involving absorption of a first UVA photon by an adequate sensitiser followed by triplet energy transfer to a pyrimidine (Pyr) derivative and absorption of a second UVA photon by the resulting Pyr triplet excited state. The feasibility of the proposed strategy has been demonstrated using two model reactions: (i) the Norrish-Yang photocyclisation of a tert-butyluracil and (ii) the photohydration of its uracil analogue, lacking the tert-butyl substituent.
Publisher version (URL)http://dx.doi.org/10.1039/d0ob00132e
Identifiersdoi: 10.1039/d0ob00132e
issn: 1477-0520
Appears in Collections:(ITQ) Artículos
Files in This Item:
File Description SizeFormat 
accesoRestringido.pdf15,38 kBAdobe PDFThumbnail
Show full item record
Review this work

WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.