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http://hdl.handle.net/10261/232113
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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Álvarez, Andrea | es_ES |
dc.contributor.author | Fernández Llamas, Lucía | es_ES |
dc.contributor.author | Gutiérrez, Diana | es_ES |
dc.contributor.author | Iglesias, Beatriz | es_ES |
dc.contributor.author | Rodríguez González, Ana | es_ES |
dc.contributor.author | García Suárez, María Pilar | es_ES |
dc.date.accessioned | 2021-03-02T16:34:00Z | - |
dc.date.available | 2021-03-02T16:34:00Z | - |
dc.date.issued | 2019-11-22 | - |
dc.identifier.citation | Journal of Clinical Microbiology 57: e01006-19 (2019) | es_ES |
dc.identifier.issn | 0095-1137 | - |
dc.identifier.uri | http://hdl.handle.net/10261/232113 | - |
dc.description.abstract | Even though antibiotic resistance in bacteria is a natural phenomenon, the alarming increase in pathogenic bacteria refractory to a wide range of antimicrobials is attracting attention worldwide. Indeed, the World Health Organization (WHO) has recently published a list of priority pathogens for which new antimicrobial alternatives are urgently needed. Among these pathogens, methicillin-resistant Staphylococcus aureus (MRSA) strains are perhaps the best known by the general public. In addition to its potential to acquire antibiotic resistance, S. aureus can produce a large number of virulence factors, such as hemolysins, enterotoxins, and proteases, and exhibits the ability to form biofilms as well as to evolve into different clones that can spread and colonize new environments. This review provides a brief overview of the latest options in antibacterial therapies, mainly focusing on phage therapy. In this regard, the current stage of research about antimicrobial compounds based on bacteriophages and endolysins against MRSA infections is shown and discussed. | es_ES |
dc.description.sponsorship | This study was funded by grants AGL2015-65673-R (MINECO/FEDER/EU, Spain), EU ANIWHA ERA-NET (BLAAT ID: 67)/PCIN-2017-001 (AEI/FEDER/EU, Spain), Proyecto Intramural CSIC201670E040, Proyecto Intramural CSIC 201770E016, IDI/2018/000119 (Asturias Innovation 2018 to 2020, Principado de Asturias, Spain) and FEDER/EU. P.G. and A.R. are members of the bacteriophage network FAGOMA II and the FWO Vlaanderen-funded “Phagebiotics” research community (WO.016.14) | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | American Society for Microbiology | es_ES |
dc.relation | info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/AGL2015-65673-R | es_ES |
dc.relation | info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PCIN-2017-001 | es_ES |
dc.relation | PCIN-2017-001/AEI/10.13039/501100011033 | es_ES |
dc.rights | closedAccess | es_ES |
dc.subject | Staphylococcus aureus | es_ES |
dc.subject | HA-MRSA | es_ES |
dc.subject | CA-MRSA | es_ES |
dc.subject | LA-MRSA | es_ES |
dc.subject | Antibiotic resistance | es_ES |
dc.subject | Soft-tissue infections | es_ES |
dc.subject | Osteomyelitis | es_ES |
dc.subject | Endocarditis | es_ES |
dc.subject | Phage therapy | es_ES |
dc.subject | Endolysins | es_ES |
dc.subject | Bacteriophage therapy | es_ES |
dc.subject | Bacteriophages | es_ES |
dc.subject | Endolysin | es_ES |
dc.title | Methicillin-resistant staphylococcus aureus in hospitals: Latest trends and treatments based on bacteriophages | es_ES |
dc.type | artículo | es_ES |
dc.identifier.doi | 10.1128/JCM.01006-19 | - |
dc.description.peerreviewed | Peer reviewed | es_ES |
dc.relation.publisherversion | https://doi.org/10.1128/JCM.01006-19 | es_ES |
dc.identifier.e-issn | 1098-660X | - |
dc.contributor.funder | Ministerio de Economía y Competitividad (España) | es_ES |
dc.contributor.funder | Ministerio de Ciencia, Innovación y Universidades (España) | es_ES |
dc.contributor.funder | Agencia Estatal de Investigación (España) | es_ES |
dc.contributor.funder | European Commission | es_ES |
dc.contributor.funder | Consejo Superior de Investigaciones Científicas (España) | es_ES |
dc.contributor.funder | Principado de Asturias | es_ES |
dc.relation.csic | Sí | es_ES |
oprm.item.hasRevision | no ko 0 false | * |
dc.identifier.funder | http://dx.doi.org/10.13039/501100000780 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100003329 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100011033 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100003339 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/100011941 | es_ES |
dc.contributor.orcid | Rodríguez González, Ana [0000-0002-1577-9905] | es_ES |
dc.identifier.pmid | 31578263 | - |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.openairetype | artículo | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | No Fulltext | - |
item.languageiso639-1 | en | - |
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