English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/22673
Compartir / Impacto:
Estadísticas
Add this article to your Mendeley library MendeleyBASE
Citado 180 veces en Web of Knowledge®  |  Pub MebCentral Ver citas en PubMed Central  |  Ver citas en Google académico
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Título

Interactions of gut microbiota with functional food components and nutraceuticals

AutorLaparra, José Moisés ; Sanz, Yolanda
Palabras claveGut microbiota
Functional foods
Nutraceuticals
Prebiotics
Polyunsaturated fatty acids
Phytochemicals
Fecha de publicaciónmar-2010
EditorElsevier
CitaciónPharmacological Research 61 (3): 219-225 (2010)
ResumenThe human gut is populated by an array of bacterial species, which develop important metabolic and immune functions, with a marked effect on the nutritional and health status of the host. Dietary component also play beneficial roles beyond basic nutrition, leading to the development of the functional food concept and nutraceuticals. Prebiotics, polyunsaturated fatty acids (PUFAs) and phytochemicals are the most well characterized dietary bioactive compounds. The beneficial effects of prebiotics mainly relay on their influence on the gut microbiota composition and their ability to generate fermentation products (short-chain fatty acids) with diverse biological roles. PUFAs include the ω-3 and ω-6 fatty acids, whose balance may influence diverse aspects of immunity and metabolism. Moreover, interactions between PUFAs and components of the gut microbiota may also influence their biological roles. Phytochemicals are bioactive non-nutrient plant compounds, which have raised interest because of their potential effects as antioxidants, antiestrogenics, anti-inflammatory, immunomodulatory, and anticarcinogenics. However, the bioavailability and effects of polyphenols greatly depend on their transformation by components of the gut microbiota. Phytochemicals and their metabolic products may also inhibit pathogenic bacteria while stimulate the growth of beneficial bacteria, exerting prebiotic-like effects. Therefore, the intestinal microbiota is both a target for nutritional intervention and a factor influencing the biological activity of other food compounds acquired orally. This review focuses on the reciprocal interactions between the gut microbiota and functional food components, and the consequences of these interactions on human health.
Descripción7 pages, 1 table, 1 figure.-- Online version published 13 November 2009
Versión del editorhttp://dx.doi.org/10.1016/j.phrs.2009.11.001
URIhttp://hdl.handle.net/10261/22673
DOI10.1016/j.phrs.2009.11.001
ISSN1043-6618
Aparece en las colecciones: (IATA) Artículos
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
PharmRes-Laparra-2010.pdf139,57 kBAdobe PDFVista previa
Visualizar/Abrir
Mostrar el registro completo
 



NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.