English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/225833
logo share SHARE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE
Exportar a otros formatos:


Marked changes in innate immunity associated with a mild course of COVID-19 in identical twins with athymia and absent circulating T cells

AuthorsColmenero-Velázquez, Argentina; Esteso, Gloria; Rosal, Teresa del; Calvo Apalategui, Ane; Reyburn, H. T. ; López-Granados, Eduardo
Issue Date3-Dec-2020
CitationJournal of Allergy and Clinical Immunology (2020)
AbstractWe read with interest the recent articles from Zhang et al and Bastard et al revealing impaired type I IFN immunity as a major risk for severe coronavirus disease 2019 (COVID-19)1,2; however, the relative importance of innate and adaptive immunity for viral control is difficult to evaluate.3 A diagnosis of mild COVID-19 in 2 identical twin neonates with an uncommon primary immunodeficiency (PID) that causes athymia and almost complete T-cell lymphopenia allowed study of innate immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the absence of adaptive immunity.
Publisher version (URL)https://doi.org/10.1016/j.jaci.2020.11.007
Appears in Collections:(CNB) Artículos
(VICYT) Colección Especial COVID-19
Files in This Item:
File Description SizeFormat 
accesoRestringido.pdf15,38 kBAdobe PDFThumbnail
Show full item record
Review this work

WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.