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Título

Complete analysis of the epidemiological scenario around a SARS-CoV-2 reinfection: previous infection events and subsequent transmission

AutorPérez-Lago, Laura; Pérez Latorre, Leire; Herranz, Marta; Tejerina, Francisco; Sola-Campoy, Pedro J.; Sicilia, Jon; Suárez-González, Julia; Andrés-Zayas, Cristina; Chiner-Oms, Álvaro CSIC ORCID ; Jiménez-Serrano, Santiago CSIC ORCID; García-González, Neris; Comas, Iñaki CSIC ORCID ; González-Candelas, Fernando CSIC ORCID; Martínez-Laperche, Carolina; Catalán, Pilar; Muñoz, Patricia; García de Viedma, Darío CSIC ORCID
Palabras claveCOVID-19
Reinfection
Transmission
Epidemiology
Genomics
Fecha de publicación2021
EditorAmerican Society for Microbiology
CitaciónmSphere 6(5): e00596-21 (2021)
ResumenThe first descriptions of reinfection by SARS-CoV-2 have been recently reported. However, these studies focus exclusively on the reinfected case, without considering the epidemiological context of the event. We present the first complete analysis of the epidemiological scenario around a reinfection by SARS-CoV-2, including three cases preceding the reinfection, the reinfected case per se, and the subsequent transmission to another seven cases. Our analysis is supported by host genetics, viral whole genome sequencing, phylogenomic population analysis, and refined epidemiological data obtained from in-depth interviews with the involved subjects. The reinfection involved a 53-year-old woman with asthma, with a first COVID-19 episode in April 2020 and a much more severe second episode four months and a half later, with COVID-19 seroconversion in August, and requiring hospital admission.
DescripciónOn behalf of Gregorio Marañón Microbiology-ID COVID 19 Study Group.
Versión del editorhttps://doi.org/10.1128/mSphere.00596-21
URIhttp://hdl.handle.net/10261/224908
DOI10.1128/mSphere.00596-21
E-ISSN2379-5042
Aparece en las colecciones: (IBV) Artículos
(I2SysBio) Artículos
(PTI Salud Global) Colección Especial COVID-19




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