Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/224841
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Título: | The relationship between chronic stress, hair cortisol and hypertension |
Autor: | Bautista, Leonelo Enrique; Bajwa, P. K.; Shafer, Martin Merrill; Malecki, Kristen M.C.; McWilliams, Christine A.; Palloni, Alberto CSIC ORCID | Palabras clave: | Blood pressure Chronic psychosocial stress Cortisol Hair cortisol Hypertension |
Fecha de publicación: | ago-2019 | Editor: | Elsevier | Citación: | International Journal of Cardiology Hypertension, vol. 2: 100012 | Resumen: | Inconsistencies in studies of chronic psychosocial stress and hypertension may be explained by the use of stress markers greatly influenced by circadian rhythm and transient stressors. We assessed whether hair cortisol, a marker that captures systemic cortisol over months, was independently associated with hypertension. We measured hair cortisol and blood pressure in 75 consecutive participants in the Survey of the Health of Wisconsin, using an ELISA test. Individuals with values ≥ median (78.1 pg/mg) were considered exposed. We used approximate Bayesian logistic regression, with a prior odds ratio of 1.0–4.0, to quantify the multivariate-adjusted hair cortisol-hypertension association. Participants' average age was 46.9 years; 37.3% were male; and 25.3% were hypertensive. Hypertension prevalence was 2.23 times higher in exposed (95% CI: 1.69–3.03). This finding was unlikely explained by differential measurement errors, since we conducted blinded measurements of exposure and outcome. Sensitivity analyses showed the association was unlikely explained by an unmeasured confounder, survival bias, or reverse causality bias. Findings suggest elevated hair cortisol is a risk factor for hypertension. Although feasible, the clinical value of hair cortisol as a tool for hypertension risk stratification or for monitoring the effect of chronic psychosocial stress management interventions is still uncertain. | Versión del editor: | https://doi.org/10.1016/j.ijchy.2019.100012 https://www.sciencedirect.com/science/article/pii/S2590086219300126 |
URI: | http://hdl.handle.net/10261/224841 | DOI: | 10.1016/j.ijchy.2019.100012 | E-ISSN: | 2590-0862 |
Aparece en las colecciones: | (CCHS-IEGD) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
Chronic_stress_hair_cortisol_hypertension.pdf | 560,58 kB | Adobe PDF | Visualizar/Abrir |
CORE Recommender
PubMed Central
Citations
14
checked on 21-abr-2024
SCOPUSTM
Citations
25
checked on 23-abr-2024
WEB OF SCIENCETM
Citations
20
checked on 26-feb-2024
Page view(s)
151
checked on 23-abr-2024
Download(s)
155
checked on 23-abr-2024