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Título: | Tumor Functional Heterogeneity Unraveled by scRNA-seq Technologies |
Autor: | González-Silva, Laura CSIC ORCID; Quevedo, Laura CSIC ORCID; Varela, Ignacio CSIC ORCID | Palabras clave: | Cancer functional heterogeneity Intratumor heterogeneity Single-cell sequencing Tumor microenvironment Liquid biopsy |
Fecha de publicación: | ene-2020 | Editor: | Elsevier | Citación: | Trends in Cancer 6(1): 13-19 (2020) | Resumen: | Effective cancer treatment has been precluded by the presence of various forms of intratumoral complexity that drive treatment resistance and metastasis. Recent single-cell sequencing technologies are significantly facilitating the characterization of tumor internal architecture during disease progression. New applications and advances occurring at a fast pace predict an imminent broad application of these technologies in many research areas. As occurred with next-generation sequencing (NGS) technologies, once applied to clinical samples across tumor types, single-cell sequencing technologies could trigger an exponential increase in knowledge of the molecular pathways involved in cancer progression and contribute to the improvement of cancer treatment. | Descripción: | © 2019 The Authors. | URI: | http://hdl.handle.net/10261/223668 | E-ISSN: | 2405-8033 |
Aparece en las colecciones: | (IBBTEC) Artículos |
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Tumor_Gonzalez_Art2020.pdf | 1,72 MB | Adobe PDF | Visualizar/Abrir |
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