English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/22008
Compartir / Impacto:
Estadísticas
Add this article to your Mendeley library MendeleyBASE
Ver citas en Google académico
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Título

The “Gene” Experiment in the Spanish Soyuz Mission to the International Space Station. Effects of cold transportation

AutorHerranz, Raúl ; Laván, David A.; Benguria, Alberto; Duque, Pedro; Zaballos, Ángel; Medina, F. Javier ; Van Loon, Jack JWA; Marco, Roberto ; Gasset, Gilbert; Leandro, L. J.
Palabras claveDrosophila
Microgravity
Fecha de publicación2007
CitaciónMicrogravity Science and Technology
Serie19
5/6
ResumenIf exploration of outer space is going to be a major human enterprise in the future, it is important to establish the nature of the biological response to the space environment. In one of the recent Soyuz missions to serve the ISS, the Spanish Soyuz Mission in October 2003, we sent a group of Drosophila pupae that underwent almost complete development there. Microarray analyses of the RNAs extracted from flies fixed in the ISS revealed that a relatively large set of genes (15% of the total number assayed) suffered a significant expression change in these conditions. Furthermore, the samples had to be transported to the launch site and it was necessary to slow down their development by exposing them to a lower temperature, fully compatible with pupal development. Such a pre-exposure had an effect by itself on the pattern of gene expression observed after pupal development at normal temperature, but the two environmental factors seemed to act synergistically. These findings indicate the importance of maintaining a vigorous scientific program in the ISS to understand the consequences of the modified environment in outer space on living organisms.
DescripciónManuscript version. Final Article available on the publisher site. http://www.springerlink.com/content/k5w4j8747211p13h/?p=1823d8063e69447cbbb58584de4e2425&pi=3
Versión del editor10.1007/BF02919481
URIhttp://hdl.handle.net/10261/22008
ISSN0938-0108
Aparece en las colecciones: (CIB) Artículos
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
Ref12-Herranz2007_edited.pdf282,19 kBAdobe PDFVista previa
Visualizar/Abrir
Mostrar el registro completo
 


NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.