English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/21986
COMPARTIR / IMPACTO:
Estadísticas
logo share SHARE   Add this article to your Mendeley library MendeleyBASE
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:
Título

Gene Expression Variations During Drosophila Metamorphosis in Space. The GENE Experiment in the Spanish Cervantes Mission to the ISS

AutorHerranz, Raúl ; Benguria, Alberto; Fernandez-Pineda, Emilio; Medina, F. Javier ; Gasset, Gilbert; van Loon, Jack JWA; Zaballos, Ángel; Marco, Roberto
Palabras claveDrosophila
microgravity
Fecha de publicación2005
CitaciónJ Gravit Physiol
Serie12
1
ResumenThe ISS expedition 8, a 10 days “taxi” flight Soyuz Mission to the International Space Station (ISS) to replace the two-member ISS crew, took place during October 2003. Within the Spanish Cervantes Scientific Mission, in this crew exchanging flight, some biological experiments were performed. The third member of the expedition, the Spanish born ESA astronaut Pedro Duque, returned with the Soyuz 7 capsule and the experiment containing transport box after 11 days on microgravity. In the GENE experiment, we intended to determine how microgravity affects the organism rebuilding processes that occurs during Drosophila metamorphosis. In addition to the ISS samples, some control experiments were performed including a 1g Ground control parallel to the ISS flight samples, a Random Position Machine microgravity si m u l a t e d c o n t r o l a n d a p a r a l l e l Hypergravity (10g) exposed samples experiment. We have used extracted RNA from these samples to test the differences among gene expression during Drosophila development with one of the current more powerful technology, a Drosophila complete genome microarray (version 1.0, AffymetrixTM). A preliminary analysis of the results indicates that around five hundred genes change their expression profiles being especially affected the mitochondrial ribosomal ones.
DescripciónManuscript long version, prior to reduction due to the mandatory final 2-pages published version
URIhttp://hdl.handle.net/10261/21986
ISSN1077-9248
Aparece en las colecciones: (CIB) Artículos
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
Ref9-Herranz2005_edited.pdf179,57 kBAdobe PDFVista previa
Visualizar/Abrir
Mostrar el registro completo
 


NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.