Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/218317
COMPARTIR / EXPORTAR:
SHARE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | Peña, Elvira de la | es_ES |
dc.contributor.author | Gomis, Ana | es_ES |
dc.date.accessioned | 2020-08-20T09:51:20Z | - |
dc.date.available | 2020-08-20T09:51:20Z | - |
dc.date.issued | 2019 | - |
dc.identifier.citation | TRP Channels. Methods and Protocols: 83-97 (2019) | es_ES |
dc.identifier.isbn | 978-1-4939-9445-8 | - |
dc.identifier.uri | http://hdl.handle.net/10261/218317 | - |
dc.description.abstract | The family of transient receptor potential (TRPs) channels contains 28 mammalian members, each a unique cellular sensor that responds to a wide variety of external and internal signals. TRP channels are expressed by most mammalian cells, where they are involved in many different physiological functions. Canonical TRP channels (TRPCs) form a family of nonselective cationic channels, although with greater selectivity for Ca2+. This family is made up of seven members (TRPC1-7), all of which contain a TRP box in the carboxyl terminal and 3-4 ankyrin repeats in the amino terminal. While these channels share some similar properties, they display diverse gating mechanisms and are involved in different signaling pathways (Gees M et al., Compr Physiol, 2012). The activation or inhibition of these channels has been studied using different approaches and techniques. Here, we characterize the activation of the TRPC5 channel expressed in a heterologous system, using calcium imaging and the patch-clamp technique in whole-cell configuration. | es_ES |
dc.description.sponsorship | This work was supported by funds from the Spanish MINECO, SAF2016-77233-R cofinanced by the European Regional Development Fund (ERDF), and the “Severo Ochoa” Program for Centers of Excellence in R&D SEV-2013-0317. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Springer Nature | es_ES |
dc.relation | info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/SAF2016-77233-R | es_ES |
dc.relation | info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/SEV-2013-0317 | es_ES |
dc.relation.ispartofseries | Methods in Molecular Biology 1987 | es_ES |
dc.rights | closedAccess | es_ES |
dc.subject | Intracellular calcium recordings | es_ES |
dc.subject | Patch clamp | es_ES |
dc.subject | Osmomechanical stimulation | es_ES |
dc.subject | TRP channels | es_ES |
dc.title | Characterization of TRPC channels in a heterologous system using calcium imaging and the patch-clamp technique | es_ES |
dc.type | capítulo de libro | es_ES |
dc.identifier.doi | 10.1007/978-1-4939-9446-5_6 | - |
dc.description.peerreviewed | Peer reviewed | es_ES |
dc.relation.publisherversion | https://doi.org/10.1007/978-1-4939-9446-5_6 | es_ES |
dc.contributor.funder | Ministerio de Economía y Competitividad (España) | es_ES |
dc.contributor.funder | European Commission | es_ES |
dc.relation.csic | Sí | es_ES |
oprm.item.hasRevision | no ko 0 false | * |
dc.identifier.funder | http://dx.doi.org/10.13039/501100000780 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100003329 | es_ES |
dc.type.coar | http://purl.org/coar/resource_type/c_3248 | es_ES |
item.openairetype | capítulo de libro | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | No Fulltext | - |
item.languageiso639-1 | en | - |
Aparece en las colecciones: | (IN) Libros y partes de libros |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
accesoRestringido.pdf | 59,24 kB | Adobe PDF | Visualizar/Abrir |
CORE Recommender
Page view(s)
119
checked on 19-abr-2024
Download(s)
20
checked on 19-abr-2024
Google ScholarTM
Check
Altmetric
Altmetric
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.