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Molecular mechanisms controlling axon guidance at the optic chiasm

Other TitlesMécanismes moléculaires contrôlant le guidage axonal au chiasma optique
AuthorsHerrera, Eloisa
Issue Date2019
CitationNeuroFrance 2019
AbstractThe proper formation of the visual pathway during development is essential for normal vision in the adult individual. There are several points along this pathway where visual axons face ”choices' in their direction of growth. One of these decision points is the optic chiasm. At this region some retinal axons decussate and cross the midline while some others make a turn to project to the ipsilateral hemisphere. Along the years, my laboratory has identified many molecules involved in axon midline crossing and avoidance. We have also found very recently an additional type of ganglion cells that, instead of projecting to the brain, transiently extend from one retina to the other by the action of guidance molecules at the optic chiasm level. My talk will focus on the molecular mechanisms that orchestrate the three different axonal decisions at this particular choice point.
DescriptionResumen del trabajo presentado al International Meeting NeuroFrance, celebrado en Marsella del 22 al 24 de mayo de 2019.
Appears in Collections:(IN) Comunicaciones congresos
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