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Title

Non-muscle myosin II activation: adding a classical touch to ROCK

AuthorsCarmena, Ana
KeywordsNon-muscle myosin II
Eph signaling
Drosophila
Issue Date2019
PublisherTaylor & Francis
CitationSmall GTPases 25: 1-6 (2019)
AbstractNon-muscle myosin II molecules are actin-binding proteins with ATPase activity, this latter capacity providing the energy required for actin filament cross-linking and contraction. The activation of these molecular motors relies on direct phosphorylation at conserved sites through different protein kinases, including the Rho-associated coiled coil-containing kinase (ROCK). In the light of some recent results found in our lab, we comment on the necessity of additional regulatory mechanisms to control the subcellular distribution of non-muscle myosin II proteins to ensure their full activation.
Publisher version (URL)https://doi.org/10.1080/21541248.2019.1671148
URIhttp://hdl.handle.net/10261/217927
DOI10.1080/21541248.2019.1671148
ISSN2154-1248
E-ISSN2154-1256
Appears in Collections:(IN) Artículos
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