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Glucose metabolism takes center stage in epithelial-mesenchymal plasticity

AuthorsKass Youssef, Khalil; Nieto, M. Ángela
Issue Date2020
CitationDevelopmental Cell 53(2): 133-135 (2020)
AbstractAerobic glycolysis, or Warburg effect, has been associated with pathologies such as cancer. In this issue of Developmental Cell, Bhattacharya et al. show that aerobic glycolysis is required for neural crest migration in development. These findings point to a link between glucose metabolism and epithelial-mesenchymal plasticity in development and disease.
DescriptionRefers to: Debadrita Bhattacharya, Ana Paula Azambuja, Marcos Simoes-Costa Metabolic Reprogramming Promotes Neural Crest Migration via Yap/Tead Signaling Developmental Cell, Volume 53, Issue 2, 20 April 2020, Pages 199-211.e6
Publisher version (URL)https://doi.org/10.1016/j.devcel.2020.03.021
Appears in Collections:(IN) Artículos
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