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Title

An effective one-pot synthesis of 5-substituted tetronic acids

AuthorsTejedor, David ; López, Gloria V.; García-Tellado, Fernando ; Marrero-Tellado, José Juan ; Armas, Pedro de ; Terrero, David
Issue Date2003
PublisherAmerican Chemical Society
CitationJournal of Organic Chemistry 68(8): pp. 3363-3365 (2003)
AbstractAn expeditions one-pot synthesis of 5-substituted tetronic acids from aldehydes and terminal conjugated alkyne as starting materialñs is described. THe entire process embodies two consecutive chemical events; a catalytic domino reaction to build the 1,3-dioxolane scaffolds 5 and a two-step acid-catalyzed trans-acetalization-lactonization reaction to furnish the tetronic acid derivatives 6.
URIhttp://hdl.handle.net/10261/21749
ISSN0022-3263
Appears in Collections:(IPNA) Artículos
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