Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/217000
COMPARTIR / EXPORTAR:
SHARE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Título: | Reaction mechanisms and applications of aryl-alcohol oxidase |
Autor: | Serrano, Ana CSIC ORCID; Carro, Juan ; Martínez, Ángel T. CSIC ORCID | Palabras clave: | GMC oxidoreductases Steroselective mechanism Aryl-alcohols Secondary alcohols Lignin biodegradation Dye decolorization Deracemization 2,5-Furandicarboxylic production Enzymatic cascades Flavor synthesis |
Fecha de publicación: | 18-jul-2020 | Editor: | Elsevier | Citación: | The Enzymes (2020) | Resumen: | Aryl-alcohol oxidases (AAO) constitute a family of FAD-containing enzymes, included in the glucose-methanol-choline oxidase/dehydrogenase superfamily of proteins. They are commonly found in fungi, where their eco-physiological role is to produce hydrogen peroxide that activates ligninolytic peroxidases in white-rot (lignin-degrading) basidiomycetes or to trigger the Fenton reactions in brown-rot (carbohydrate-degrading) basidiomycetes. These enzymes catalyze the oxidation of a plethora of aromatic, and some aliphatic, polyunsaturated alcohols bearing conjugated primary hydroxyl group. Besides, the enzymes show activity on the hydrated forms of the corresponding aldehydes. Some AAO features, such as the broad range of substrates that it can oxidize (with the only need of molecular oxygen as co-substrate) and its stereoselective mechanism, confer good properties to these enzymes as industrial biocatalysts. In fact, AAO can be used for different biotechnological applications, such as flavor synthesis, secondary alcohol deracemization and oxidation of furfurals for the production of furandicarboxylic acid as a chemical building block. Also, AAO can participate in processes of interest in the wood biorefinery and textile industries as an auxiliary enzyme providing hydrogen peroxide to ligninolytic or dye-decolorizing peroxidases. Both rational design and directed molecular evolution have been employed to engineer AAO for some of the above biotechnological applications. | Descripción: | 26 p.-7 fig.-2 tab. The Enzymes (2020) | Versión del editor: | https://doi.org/10.1016/bs.enz.2020.05.005 | URI: | http://hdl.handle.net/10261/217000 | DOI: | 10.1016/bs.enz.2020.05.005 | ISSN: | 0423-2607 | E-ISSN: | 1874-6047 |
Aparece en las colecciones: | (CIB) Libros y partes de libros |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
accesoRestringido.pdf | Restringido | 15,38 kB | Adobe PDF | Visualizar/Abrir |
CORE Recommender
Page view(s)
183
checked on 28-mar-2024
Download(s)
31
checked on 28-mar-2024
Google ScholarTM
Check
Altmetric
Altmetric
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.