Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/216533
Share/Export:
logo share SHARE logo core CORE BASE
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE

Invite to open peer review
DC FieldValueLanguage
dc.contributor.authorSerrano-Bueno, Gloria-
dc.contributor.authorSaid, Fátima E.-
dc.contributor.authorReyes, Pedro de los-
dc.contributor.authorLucas-Reina, Eva-
dc.contributor.authorOrtíz-Marchena, M. Isabel-
dc.contributor.authorRomero, José M.-
dc.contributor.authorValverde, Federico-
dc.date.accessioned2020-07-13T12:20:09Z-
dc.date.available2020-07-13T12:20:09Z-
dc.date.issued2020-
dc.identifierdoi: 10.1111/tpj.14590-
dc.identifierissn: 1365-313X-
dc.identifier.citationPlant Journal 101: 1287- 1302 (2020)-
dc.identifier.urihttp://hdl.handle.net/10261/216533-
dc.description.abstractFlowering time is a key process in plant development. Photoperiodic signals play a crucial role in the floral transition in Arabidopsis thaliana, and the protein CONSTANS (CO) has a central regulatory function that is tightly regulated at the transcriptional and post-translational levels. The stability of CO protein depends on a light-driven proteasome process that optimizes its accumulation in the evening to promote the production of the florigen FLOWERING LOCUS T (FT) and induce seasonal flowering. To further investigate the post-translational regulation of CO protein we have dissected its interactome network employing in vivo and in vitro assays and molecular genetics approaches. The immunophilin FKBP12 has been identified in Arabidopsis as a CO interactor that regulates its accumulation and activity. FKBP12 and CO interact through the CCT domain, affecting the stability and function of CO. fkbp12 insertion mutants show a delay in flowering time, while FKBP12 overexpression accelerates flowering, and these phenotypes can be directly related to a change in accumulation of FT protein. The interaction is conserved between the Chlamydomonas algal orthologs CrCO–CrFKBP12, revealing an ancient regulatory step in photoperiod regulation of plant development.-
dc.languageeng-
dc.publisherBlackwell Publishing-
dc.relation.isversionofPostprint-
dc.rightsopenAccessen_EN
dc.subjectFloral transition-
dc.subjectPhotoperiodic flowering-
dc.subjectCONSTANS-
dc.subjectPosttranslational modification-
dc.subjectProtein stability-
dc.subjectFKBP12-
dc.titleCONSTANS–FKBP12 interaction contributes to modulation of photoperiodic flowering in Arabidopsis-
dc.typeartículo-
dc.identifier.doi10.1111/tpj.14590-
dc.relation.publisherversionhttp://dx.doi.org/10.1111/tpj.14590-
dc.embargo.terms2020-10-29-
dc.date.updated2020-07-13T12:20:09Z-
dc.relation.csic-
dc.type.coarhttp://purl.org/coar/resource_type/c_6501es_ES
item.openairetypeartículo-
item.fulltextWith Fulltext-
item.grantfulltextopen-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
Appears in Collections:(IBVF) Artículos
Files in This Item:
File Description SizeFormat
TPJ-01121-2019_Proof_fl.pdf3,95 MBAdobe PDFThumbnail
View/Open
Show simple item record

CORE Recommender

SCOPUSTM   
Citations

16
checked on May 17, 2024

WEB OF SCIENCETM
Citations

17
checked on Feb 23, 2024

Page view(s)

146
checked on May 27, 2024

Download(s)

138
checked on May 27, 2024

Google ScholarTM

Check

Altmetric

Altmetric


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.