English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/216318
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE
Exportar a otros formatos:


Evaluation of the circadian rhythm of anti-Leishmania IgG2 and IgA antibodies in serum and saliva of dogs with clinical leishmaniosis

AuthorsCantos-Barreda, A.; Escribano, D.; Egui, Adriana; López López, Manuel Carlos; Cerón, J.J.; Bernal, L.J.; Martínez-Subiela, S.
KeywordsAnti-Leishmania antibodies
Circadian rhythm
Issue Date2020
CitationComparative Immunology, Microbiology and Infectious Diseases 68 (2020)
AbstractIn this study, the circadian rhythm of IgG2 and IgA specific antibodies in serum and saliva samples of 6 dogs experimentally infected with Leishmania infantum was assessed. Sampling was performed at 8.00, 12.00, 16.00, 20.00, and 00.00 h on two consecutive days. Anti-Leishmania antibody levels in serum were expressed without any correction, whereas in saliva were shown in different ways: without any correction, adjusted by protein concentration and corrected by the salivary flow rate. No significant differences in anti-Leishmania IgG2 antibody levels in serum and saliva samples with or without correction were found. Significant differences were found when anti-Leishmania IgA levels were corrected by the salivary flow rate. In addition, a greater intra-individual variation of antibody levels was observed in saliva than in serum. However, this variation did not modify the serological status of the dogs. Therefore, it could be concluded that there is no circadian rhythm in serum and saliva samples and sampling can be performed at any time of the day.
Publisher version (URL)http://dx.doi.org/10.1016/j.cimid.2019.101389
Identifiersdoi: 10.1016/j.cimid.2019.101389
issn: 0147-9571
e-issn: 1878-1667
Appears in Collections:(IPBLN) Artículos
Files in This Item:
File Description SizeFormat 
accesoRestringido.pdf15,38 kBAdobe PDFThumbnail
Show full item record
Review this work

WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.