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Electrochemical Biosensors Based on Membrane-Bound Enzymes in Biomimetic Configurations

AuthorsAlvarez-Malmagro, Julia; García-Molina, Gabriel; López de Lacey, Antonio
Biomimetic membranes
Membrane-bound enzymes
Issue Date16-Jun-2020
PublisherMultidisciplinary Digital Publishing Institute
CitationSensors 20(12): 3393 (2020)
AbstractIn nature, many enzymes are attached or inserted into the cell membrane, having hydrophobic subunits or lipid chains for this purpose. Their reconstitution on electrodes maintaining their natural structural characteristics allows for optimizing their electrocatalytic properties and stability. Different biomimetic strategies have been developed for modifying electrodes surfaces to accommodate membrane-bound enzymes, including the formation of self-assembled monolayers of hydrophobic compounds, lipid bilayers, or liposomes deposition. An overview of the different strategies used for the formation of biomimetic membranes, the reconstitution of membrane enzymes on electrodes, and their applications as biosensors is presented.
Description© 2020 by the authors.
Publisher version (URL)https://doi.org/10.3390/s20123393
Appears in Collections:(ICP) Artículos
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