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Title

Guillain-Barré and Alpha-gal syndromes: Saccharides-induced immune responses

AuthorsFuente, José de la ; Pacheco, Iván; Contreras, Marinela; Mateos-Hernández, Lourdes ; Villar, Margarita ; Cabezas-Cruz, Alejandro
KeywordsImmunology
Vaccine
Tick
Infectious disease
Galactose
Allergy
Alpha gal
Issue Date2019
PublisherXia & He Publishing
CitationExploratory Research and Hypothesis in Medicine 4: 87–89 (2019)
AbstractThe molecular interactions between hosts, vectors and pathogens drive the etiology of infectious diseases. At first sight, the Guillain-Barré and Alpha-Gal syndromes have quite different etiologies but, as proposed here, a closer look into the immune response to galactose-containing oligosaccharide structures that characterizes these two diseases reveals striking commonalities. In this Opinion paper, we address the main molecular drivers of two apparently unrelated diseases, and how the characterization of the immune response and immunological tolerance would advance the control and prevention of these diseases.
Publisher version (URL)https://doi.org/10.14218/ERHM.2019.00027
URIhttp://hdl.handle.net/10261/215595
DOIhttp://dx.doi.org/10.14218/ERHM.2019.00027
E-ISSN2472-0712
Appears in Collections:(IREC) Artículos
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