English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/215553
logo share SHARE   Add this article to your Mendeley library MendeleyBASE
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE
Exportar a otros formatos:


Biotechnological production of zeaxanthin by an Antarctic Flavobacterium: Evaluation of culture conditions

AuthorsVila, Eugenia; Hornero-Méndez, Dámaso ; Lareo, Claudia; Saravia, Verónica
Flavobacteriumexperimental design
Issue Date22-May-2020
CitationJournal of Biotechnology 319: 54 (2020)
AbstractStatistical experimental designs were used to formulate a culture medium for zeaxanthin production by an Antarctic Flavobacterium sp. P8 strain. Eleven nutritional factors were assayed in shaken flasks. The effect of temperature on zeaxanthin and carotenoid production was also studied. Peptone, yeast extract, and sodium chloride were the nutrients that caused the principal impact on the biomass growth. These components were further studied to enhance zeaxanthin and total carotenoid concentrations. Although a high production rate of zeaxanthin and carotenoids was achieved, the aerobic characteristics of the bacterial strain and the oxygen requirements for zeaxanthin biosynthesis incorporate a factor that requires additional consideration. Scaling up the process to a 5 L-bioreactor that increased dissolved oxygen availability resulted in a 4.5-fold increase in the total carotenoid content and an almost 9-fold increase in zeaxanthin, which represented 98% of the total carotenoids produced. The results reveal that Flavobacterium sp. P8 is a promising strain for zeaxanthin production.
Description24 Páginas.-- 1 Figura.-- 7 Tablas
Publisher version (URL)http://dx.doi.org/10.1016/j.jbiotec.2020.05.014
Appears in Collections:(IG) Artículos
Files in This Item:
File Description SizeFormat 
PostP_2020_JB_V319_P54.pdf Embargoed until May 22, 2021Artículo principal721,17 kBAdobe PDFThumbnail
View/Open    Request a copy
Show full item record
Review this work

WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.