Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/215040
COMPARTIR / EXPORTAR:
logo share SHARE logo core CORE BASE
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE

Invitar a revisión por pares abierta
Título

Evaluating the association between artificial light-at-night exposure and breast and prostate cancer risk in Spain (Mcc-spain study)

AutorGarcia-Saenz, A.; Sánchez de Miguel, A.; Espinosa, Ana CSIC ORCID; Valentin, A.; Aragonés, N.; Llorca, J.; Amiano, P.; Sánchez, V. M.; Guevara, M.; Capelo, R.; Tardón, A.; Peiró-Perez, R.; Jiménez-Moleón, J. J.; Roca-Barceló, A.; Pérez-Gómez, Beatriz; Dierssen-Sotos, Trinidad; Fernández-Villa, T.; Moreno-Iribas, C.; Moreno, Vicente; Pérez, J. G.; Castaño-Vinyals, G.; Pollán, M.; Aubé, M.; Kogevinas, M.
Fecha de publicación2018
CitaciónEnvironmental Health Perspectives 126(4): 047011 (2018)
ResumenBACKGROUND: Night shift work, exposure to light at night (ALAN) and circadian disruption may increase the risk of hormone-dependent cancers. OBJECTIVES: We evaluated the association of exposure to ALAN during sleeping time with breast and prostate cancer in a population based multicase-control study (MCC-Spain), among subjects who had never worked at night. We evaluated chronotype, a characteristic that may relate to adaptation to light at night. METHODS: We enrolled 1,219 breast cancer cases, 1,385 female controls, 623 prostate cancer cases, and 879 male controls from 11 Spanish regions in 2008-2013. Indoor ALAN information was obtained through questionnaires. Outdoor ALAN was analyzed using images from the International Space Station (ISS) available for Barcelona and Madrid for 2012-2013, including data of remotely sensed upward light intensity and blue light spectrum information for each geocoded longest residence of each MCC-Spain subject. RESULTS: Among Barcelona and Madrid participants with information on both indoor and outdoor ALAN, exposure to outdoor ALAN in the blue light spectrum was associated with breast cancer [adjusted odds ratio (OR) for highest vs. lowest tertile, OR=1.47; 95% CI: 1.00, 2.17] and prostate cancer (OR=2.05; 95% CI: 1.38, 3.03). In contrast, those exposed to the highest versus lowest intensity of outdoor ALAN were more likely to be controls than cases, particularly for prostate cancer. Compared with those who reported sleeping in total darkness, men who slept in “quite illuminated” bedrooms had a higher risk of prostate cancer (OR=2.79; 95% CI: 1.55, 5.04), whereas women had a slightly lower risk of breast cancer (OR=0.77; 95% CI: 0.39, 1.51). CONCLUSION: Both prostate and breast cancer were associated with high estimated exposure to outdoor ALAN in the blue-enriched light spectrum.© 2018, Public Health Services, US Dept of Health and Human Services. All rights reserved.
DescripciónOpen-access, published with support from the National Institute of Environmental Health Sciences, National Institutes of Health.
Versión del editorhttp://dx.doi.org/10.1289/EHP1837
URIhttp://hdl.handle.net/10261/215040
DOI10.1289/EHP1837
Identificadoresdoi: 10.1289/EHP1837
issn: 1552-9924
Aparece en las colecciones: (IAA) Artículos




Ficheros en este ítem:
Fichero Descripción Tamaño Formato
IAA_2018EHP1837.pdf2,39 MBAdobe PDFVista previa
Visualizar/Abrir
Mostrar el registro completo

CORE Recommender

PubMed Central
Citations

43
checked on 06-mar-2024

SCOPUSTM   
Citations

127
checked on 16-mar-2024

WEB OF SCIENCETM
Citations

117
checked on 25-feb-2024

Page view(s)

133
checked on 17-mar-2024

Download(s)

81
checked on 17-mar-2024

Google ScholarTM

Check

Altmetric

Altmetric


Artículos relacionados:


NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.