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Adults with familial hypercholesterolaemia have healthier dietary and lifestyle habits compared with their non-affected relatives: the SAFEHEART study

AuthorsArroyo-Olivares, Raquel; Alonso, Rodrigo; Quintana-Navarro, Gracia; Fuentes-Jiménez, Francisco; Mata, Nelva; Muñiz Grijalvo, Ovidio; Diaz-Diaz, Jose Luis; Zambón, Daniel; Arrieta, Francisco; García-Cruces, Jesús; Garrido-Sanjuan, Juan A.; Banegas, José R.; Mata, Pedro
KeywordsFamilial hypercholesterolaemia
Fatty acids
Mediterranean diet
Physical activity
Issue DateJun-2019
PublisherCambridge University Press
CitationPublic Health Nutrition 22(8): 1433-1443 (2019)
Abstract[Objective] Healthy lifestyle habits are the cornerstone in the management offamilial hypercholesterolaemia (FH). Nevertheless, dietary studies on FH-affectedpopulations are scarce. The present study analyses dietary habits, adherence to aMediterranean diet pattern and physical activity in an adult population with FHand compares them with their non-affected relatives.
[Design] Cross-sectional study.
[Setting] Data came from SAFEHEART, a nationwide study in Spain.
[Participants] Individuals (n 3714) aged ≥18 years with a genetic diagnosis of FH (n2736) and their non-affected relatives (n 978). Food consumption was evaluated using a validated FFQ.
[Results] Total energy intake was lower in FH patients v. non-affected relatives (P<0·005). Percentage of energy from fats was also lower in the FH population (35 % in men, 36 % in women) v. those non-affected (38 % in both sexes, P<0·005), due to the lower consumption of saturated fats (12·1 % in FH patients, 13·2 % in non-affected, P<0·005). Consumption of sugars was lower in FH patients v. non-affected relatives (P<0·05). Consumption of vegetables, fish and skimmed milk was higher in the FH population (P<0·005). Patients with FH showed greater adherence to a Mediterranean diet pattern v. non-affected relatives (P<0·005). Active smoking was lower and moderate physical activity was higher in people with FH, especially women (P<0·005).
[Conclusions] Adult patients with FH report healthier lifestyles than their non-affected family members. They eat a healthier diet, perform more physical activity and smoke less. However, this patient group’s consumption of saturated fats and sugars still exceeds guidelines.
Publisher version (URL)http://dx.doi.org/10.1017/S1368980018003853
Identifiersdoi: 10.1017/S1368980018003853
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