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Title

Adriatoxin-B, the first C13 terminal truncated YTX analogue obtained from dinoflagellates

AuthorsDomínguez, Humberto J.; Souto, María L.; Norte, Manuel; Hernández Daranas, Antonio ; Fernández, José J.
KeywordsAdriatoxin
Yessotoxin
Marine toxins
DSP syndrome
Marine polyethers
Issue Date6-Jul-2010
PublisherElsevier
CitationToxicon 55(8): 1484-1490 (2010)
AbstractAdriatoxin-B (ATX-B) is the first C13 terminal truncated YTX analogous metabolite that was isolated from large-scale cultures of the dinoflagellate Protoceratium reticulatum. The structure and conformational behavior of ATX-B was elucidated by a combination of NMR spectroscopy experiments and a conformational analysis. The isolation of this metabolite, which possesses a clear structural relationship with adriatoxin, supports the idea that the real source of these cut down substances is in the microalgae and not in the mollusks, via metabolic degradation like it has been assumed until now.
Publisher version (URL)https://doi.org/10.1016/j.toxicon.2010.02.029
URIhttp://hdl.handle.net/10261/213301
ISSN0041-0101
10.1016/j.toxicon.2010.02.029
E-ISSN1879-3150
Appears in Collections:(IPNA) Artículos
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