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Genetic Basis of Vasculitides with Neurologic Involvement

AuthorsCarmona, F. D.; López-Mejías, Raquel; Márquez, Ana; Martín, J.; González-Gay, M. A.
KeywordsGenetic risk factors
Genome-wide association studies
Nervous system
Issue Date2019
CitationNeurologic Clinics
Abstract“Vasculitides are a heterogeneous group of inflammatory diseases of blood vessels in which genetic variation plays an important role in their susceptibility and clinical spectrum. Because of the use of novel technologies and the increase of the sample size of the study cohorts, the knowledge of the genetic background of vasculitides has considerably expanded during the last years. However, few insights have been obtained regarding the genetics underlying severe clinical phenotypes, such as those related to the nervous system. In this review the authors provide an updated overview of the genetic landscape behind vasculitis predisposition and development of neurologic manifestations.”
Publisher version (URL)http://dx.doi.org/10.1016/j.ncl.2019.01.006
Identifiersdoi: 10.1016/j.ncl.2019.01.006
issn: 0733-8619
e-issn: 1557-9875
Appears in Collections:(IPBLN) Artículos
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