English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/211737
Share/Impact:
Statistics
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE
Exportar a otros formatos:

Title

The European Register of Cystic Echinococcosis, ERCE: state-of-the-art five years after its launch

Other TitlesParasites & vectors, 13: 236
AuthorsRossi, Patrizia; Tamarozzi, Francesca; Galati, Fabio; Akhan, Okan; Cretu, Carmen Michaela; Vutova, Kamenna; Siles Lucas, Mar ; Brunetti, Enrico; Casulli, Adriano; ERCE network
KeywordsCystic echinococcosis
Register
Public health awareness
Case series
Issue Date2020
PublisherBioMed Central
CitationParasites and Vectors 13: 236 (2020)
AbstractBackground: The real burden of human cystic echinococcosis (CE) remains elusive, due to the peculiar characteristics of the disease and the heterogeneous and incomplete data recording of clinical cases. Furthermore, official notification systems do not collect pivotal clinical information, which would allow the comparison of different treatment outcomes, and thus circumvent the difficulty of implementing clinical trials for CE. The Italian Register of CE (RIEC) was launched in 2012 and expanded in 2014 into the European Register of CE (ERCE). The primary aim of the ERCE was to highlight the magnitude of CE underreporting, through the recording of cases that were not captured by official records. We present an overview of data collated in the ERCE and discuss its future, five years after its inception. Methods: The ERCE database was explored on March 31st 2019; data concerning participating centres and registered cases were descriptively analysed. Results: Forty-four centres from 15 countries (7 non-European) were affiliated to the ERCE. Thirty-four centres (77%) registered at least one patient; of these, 18 (53%) recorded at least one visit within the past 18 months. A total of 2097 patients were registered, 19.9% of whom were immigrants. Cyst characteristics were reported for at least one cyst at least in one visit in 1643 (78.3%) patients, and cyst staging was used by 27 centres. In total, 3386 cysts were recorded at first registration; mostly located in the liver (75.5%). Data concerning clinical management could be analysed for 920 “cyst stage-location-management” observations, showing great heterogeneity in the implementation of the stage-specific management approach recommended by the WHO. Conclusions: The ERCE achieved its goal in showing that CE is a relevant but neglected public health problem in Europe and beyond, since a proportion of patients reaching medical attention are not captured by official notification systems. The ERCE may provide a valuable starting platform to complement hospital-derived data, to obtain a better picture of the epidemiology of clinical CE, and to collect clinical data for the issue of evidence-based recommendations. The ERCE will be expanded into the International Register of CE (IRCE) and restructured aiming to overcome its current criticalities and fulfil these aims
Description10 páginas, 3 tablas, 4 figuras
Publisher version (URL)http://dx.doi.org/10.1186/s13071-020-04101-6
URIhttp://hdl.handle.net/10261/211737
DOI10.1186/s13071-020-04101-6
E-ISSN1756-3305
Appears in Collections:(IRNASA) Artículos
Files in This Item:
File Description SizeFormat 
the European Register of Cystic Echinococcosis.pdfArtículo principal1,48 MBAdobe PDFThumbnail
View/Open
Show full item record
Review this work
 

Related articles:


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.