English
español
Please use this identifier to cite or link to this item:
http://hdl.handle.net/10261/211681
Share/Impact:
Statistics |
![]() ![]() |
|
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | ||
|
Title: | Dye-Loaded Quatsomes Exhibiting FRET as Nanoprobes for Bioimaging |
Authors: | Morla Folch, Judit; Vargas Nadal, Guillem; Zhao, Tinghan; Sissa, Cristina; Ardizzone, Antonio ![]() ![]() ![]() |
Keywords: | Bioimaging Fluorescent organic nanoparticles FRET Quatsomes Bioprobes |
Issue Date: | 6-May-2020 |
Publisher: | American Chemical Society |
Citation: | ACS Applied Materials and Interfaces 12(18): 20253-20262 (2020) |
Abstract: | Fluorescent organic nanoparticles (FONs) are emerging as an attractive alternative to the well-established fluorescent inorganic nanoparticles or small organic dyes. Their proper design allows one to obtain biocompatible probes with superior brightness and high photostability, although usually affected by low colloidal stability. Herein, we present a type of FONs with outstanding photophysical and physicochemical properties in-line with the stringent requirements for biomedical applications. These FONs are based on quatsome (QS) nanovesicles containing a pair of fluorescent carbocyanine molecules that give rise to Förster resonance energy transfer (FRET). Structural homogeneity, high brightness, photostability, and high FRET efficiency make these FONs a promising class of optical bioprobes. Loaded QSs have been used for in vitro bioimaging, demonstrating the nanovesicle membrane integrity after cell internalization, and the possibility to monitor the intracellular vesicle fate. Taken together, the proposed QSs loaded with a FRET pair constitute a promising platform for bioimaging and theranostics. |
Publisher version (URL): | http://dx.doi.org/10.1021/acsami.0c03040 |
URI: | http://hdl.handle.net/10261/211681 |
ISSN: | 1944-8244 |
Appears in Collections: | (ICMAB) Artículos |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Morla_ACSApplMatInt_2020_editorial.pdf | 5,48 MB | Adobe PDF | ![]() View/Open |
Show full item record
Review this work
Review this work
WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.