English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/210915
Share/Impact:
Statistics
logo share SHARE   Add this article to your Mendeley library MendeleyBASE
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:

Title

The European Register of Cystic Echinococcosis, ERCE: state-of-the-art five years after its launch

AuthorsRossi, Patrizia; Tamarozzi, Francesca; Galati, Fabio; Akhan, Okan; Cretu, Carmen M; Vutova, Kamenna; Siles Lucas, Mar ; Brunetti, Enrico; Casulli, Adriano
KeywordsCystic echinococcosis
Register
Public health awareness
Case series
Issue Date7-May-2020
PublisherBioMed Central
CitationParasites & Vectors. 2020 May 07;13(1):236
AbstractAbstract Background The real burden of human cystic echinococcosis (CE) remains elusive, due to the peculiar characteristics of the disease and the heterogeneous and incomplete data recording of clinical cases. Furthermore, official notification systems do not collect pivotal clinical information, which would allow the comparison of different treatment outcomes, and thus circumvent the difficulty of implementing clinical trials for CE. The Italian Register of CE (RIEC) was launched in 2012 and expanded in 2014 into the European Register of CE (ERCE). The primary aim of the ERCE was to highlight the magnitude of CE underreporting, through the recording of cases that were not captured by official records. We present an overview of data collated in the ERCE and discuss its future, five years after its inception. Methods The ERCE database was explored on March 31st 2019; data concerning participating centres and registered cases were descriptively analysed. Results Forty-four centres from 15 countries (7 non-European) were affiliated to the ERCE. Thirty-four centres (77%) registered at least one patient; of these, 18 (53%) recorded at least one visit within the past 18 months. A total of 2097 patients were registered, 19.9% of whom were immigrants. Cyst characteristics were reported for at least one cyst at least in one visit in 1643 (78.3%) patients, and cyst staging was used by 27 centres. In total, 3386 cysts were recorded at first registration; mostly located in the liver (75.5%). Data concerning clinical management could be analysed for 920 “cyst stage-location-management” observations, showing great heterogeneity in the implementation of the stage-specific management approach recommended by the WHO. Conclusions The ERCE achieved its goal in showing that CE is a relevant but neglected public health problem in Europe and beyond, since a proportion of patients reaching medical attention are not captured by official notification systems. The ERCE may provide a valuable starting platform to complement hospital-derived data, to obtain a better picture of the epidemiology of clinical CE, and to collect clinical data for the issue of evidence-based recommendations. The ERCE will be expanded into the International Register of CE (IRCE) and restructured aiming to overcome its current criticalities and fulfil these aims.
URIhttps://doi.org/10.1186/s13071-020-04101-6
http://hdl.handle.net/10261/210915
Appears in Collections:Colección Biomed Central-Chemistry Central-Springer Open
Files in This Item:
File Description SizeFormat 
13071_2020_Article_4101.pdf1,48 MBAdobe PDFThumbnail
View/Open
Show full item record
Review this work
 


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.