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Searching for genes required for Drosophila ring gland development

AuthorsGarcía Ferrés, Mar Silvia; Castelli-Gair Hombría, James
Issue Date23-Oct-2019
CitationEuropean Developmental Biology Congress (2019)
AbstractThe ring gland is the major endocrine organ of the fly, formed by the fusion of three independent glands: the corpora allata, the prothoracic glands and the corpora cardiaca. The primordium of each gland is specified independently during embryogenesis in three different cephalic positions from where they migrate to converge at the anterior tip of the aorta. During this process, both the corpora allata and the prothoracic gland primordia experience an epithelial to mesenchymal transition induced by the activation of snail. The genetic network downstream of this event is yet unknown, as well as the factors controlling the directed migration of these cells to their final position. To identify genes involved in ring gland development, we are using a deficiency screening approach. As a complementary method, we are also implementing the Translating Ribosome Affinity Purification technique to identify the translatome of the endocrine primordia. Here we present data derived from the third chromosome screening, focusing on RhoGEF pebble (pbl).
DescriptionResumen del trabajo presentado en el European Developmental Biology Congress, celebrado en Alicante (España), del 23 al 26 de octubre de 2019
Appears in Collections:(CABD) Comunicaciones congresos
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