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| Título: | 2-(Dibenzylamino)butane-1,4-dithiol (DABDT), a Friendly Disulfide-Reducing Reagent Compatible with a Broad Range of Solvents |
Autor: | Mthembu, Sinenhlanhla N.; Sharma, Anamika; Albericio, Fernando CSIC ORCID; de la Torre, Beatriz G. | Palabras clave: | DABDT Bioconjugate chemistry |
Fecha de publicación: | nov-2019 | Editor: | American Chemical Society | Citación: | Organic Letters 21 (24): 10111-10114 (2019) | Resumen: | Disulfide-reducing agents play a crucial role in bioconjugate chemistry. Herein, we describe the synthesis of a new disulfide-reducing agent [2-(dibenzylamino)butane-1,4-dithiol (DABDT)] that is conveniently prepared from inexpensive aspartic acid. Being nonmalodorous and highly soluble in a broad range of solvents, DABDT is user-friendly. We have demonstrated its performance both in solution and in the solid phase. | Versión del editor: | 10.1021/acs.orglett.9b04106 | URI: | http://hdl.handle.net/10261/209785 | DOI: | 10.1021/acs.orglett.9b04106 |
| Aparece en las colecciones: | (IQAC) Artículos |
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| 2-(Dibenzylamino)butane-1,4-dithiol (DABDT), a Friendly Disulfide-Reducing Reagent Compatible with a Broad Range of Solvents.docx | Artículo principal | 28,62 kB | Microsoft Word XML | Visualizar/Abrir |
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