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dc.contributor.authorLópez-Casas, Pedro P.es_ES
dc.contributor.authorLópez-Fernández, Luis A.es_ES
dc.contributor.authorKrimer, Dora B.es_ES
dc.contributor.authorDel Mazo, Jesúses_ES
dc.date.accessioned2020-04-24T12:36:06Z-
dc.date.available2020-04-24T12:36:06Z-
dc.date.issued2002-04-
dc.identifier.citationMech Dev 113(1):103-6 (2002)es_ES
dc.identifier.issn0925-4773-
dc.identifier.urihttp://hdl.handle.net/10261/209008-
dc.description4 p.-4 fig.es_ES
dc.description.abstractRan is a small GTP-binding protein involved in several essential roles for cell viability. This observation implies Ran might be ubiquitously expressed during development. However, Ran shows a differentiated expression pattern that is restricted to specific tissues from embryo to adult. At early embryonic stages of mouse development we found persistent Ran expression in proliferating neural tissue, neural crest derived dorsal root ganglions and sensory pits. We also showed an accumulation of Ran transcripts in main embryonic haematopoietic tissues: blood islands first and then hepatic bud. In advanced stages of development Ran is also expressed in other tissues showing a high cell turnover.es_ES
dc.description.sponsorshipThis work wassupported by grants from the CICYT: (BMC2000-1127) to J.M. and (PM-97-0138) to D.B.K.es_ES
dc.language.isoenges_ES
dc.publisherElsevieres_ES
dc.rightsclosedAccesses_ES
dc.subjectRan-GTPasees_ES
dc.subjectMousees_ES
dc.subjectEarly embryoes_ES
dc.subjectNeural tissuees_ES
dc.subjectHematopoietic tissuees_ES
dc.subjectEctoplacental conees_ES
dc.subjectSomitees_ES
dc.subjectLimb budes_ES
dc.subjectBranchial arches_ES
dc.subjectLateral nasalprocesses_ES
dc.subjectLunges_ES
dc.subjectMidgutes_ES
dc.subjectMesonephric ductes_ES
dc.subjectKidneyes_ES
dc.titleRan GTPase expression during early development of the mouse embryoes_ES
dc.typeartículoes_ES
dc.identifier.doi10.1016/s0925-4773(02)00007-2-
dc.description.peerreviewedPeer reviewedes_ES
dc.relation.publisherversionhttps://doi.org/10.1016/s0925-4773(02)00007-2es_ES
dc.identifier.e-issn1872-6356-
dc.contributor.funderComisión Interministerial de Ciencia y Tecnología, CICYT (España)es_ES
dc.relation.csices_ES
oprm.item.hasRevisionno ko 0 false*
dc.identifier.funderhttp://dx.doi.org/10.13039/501100007273es_ES
dc.contributor.orcidLópez-Casas, Pedro P. [0000-0001-9866-7361]es_ES
dc.contributor.orcidLópez-Fernández, Luis A. [0000-0003-3964-5837]es_ES
dc.contributor.orcidKrimer, Dora B. [0000-0001-9972-3994]es_ES
dc.contributor.orcidDel Mazo, Jesús [0000-0003-3269-3895]es_ES
dc.type.coarhttp://purl.org/coar/resource_type/c_6501es_ES
item.openairetypeartículo-
item.cerifentitytypePublications-
item.languageiso639-1en-
item.grantfulltextnone-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextNo Fulltext-
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