English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/208587
logo share SHARE   Add this article to your Mendeley library MendeleyBASE
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:


Better Maps for Retrograde Transmission: Novel Molecular, Synaptic and Circuit Mechanisms

AuthorsNavarrete, Marta
Issue Date24-Jul-2019
CitationCannabinoid Function in the CNS Gordon Research Conference: Dissecting the Roles and Functions of Plant-Derived Cannabinoids July 20 - 21, 2019
AbstractEndocannabinoid-mediated retrograde signaling is a fundamental counterpart of anterograde synaptic transmission throughout the CNS. However, despite decades of dedicated research, our understanding of the governing principles of endocannabinoid signaling at the molecular, synaptic and circuit levels has remained rather limited. Moreover, in the age of rapidly spreading medical and recreational use of marijuana, a consequential modulator of the endocannabinoid pathway, it is pivotal to get better insights into the neurobiological mechanisms of how cannabis products exhibit their therapeutic or adverse effects. Therefore, the major objective of the 2019 >Cannabinoid Function in the CNS> Gordon Research Conference is to showcase unpublished research data addressing the burning questions of cannabinoid research thereby stimulating the life science community to focus on solving these pending challenges: What is the molecular logic behind canonical and non-canonical cannabinoid receptor signaling distinguishing them from classical GPCR activation patterns? What are the molecular underpinnings of intracellular versus intercellular forms of endocannabinoid signaling? Why there are different types of endocannabinoids and what is the division of labor between these lipid messengers in synaptic and extrasynaptic signaling? How the different forms of endocannabinoid-mediated plasticity are integrated into specific brain circuit functions in the developing and adult brain? How emerging knowledge on aberrant forms of endocannabinoid signaling leads to the better mechanistic understanding of the pathogenesis of many neurological and psychiatric brain disorders? Finally, how medical marijuana use and how recreational cannabis abuse lead to therapeutic benefits or to neuropsychiatric diseases, respectively?
Appears in Collections:(IC) Comunicaciones congresos
Files in This Item:
File Description SizeFormat 
accesoRestringido.pdf15,38 kBAdobe PDFThumbnail
Show full item record
Review this work

WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.