Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/204109
Share/Export:
logo share SHARE logo core CORE BASE
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE
Title

Chimeric camel/human heavy-chain antibodies protect against MERS-CoV infection

AuthorsStalin Raj, V.; Okba, Nisreen M. A.; Gutierrez-Alvarez, Francisco J. ; Drabek, Dubravka; Dieren, Brenda van; Widagdo, W.; Lamers, Mart M.; Widjaja, Ivy; Fernandez-Delgado, Raúl ; Solá Gurpegui, Isabel ; Bensaid, Albert; Koopmans; Marion P.; Segalés, Joaquim; Osterhaus, Albert D. M. E.; Bosch, Berend Jan; Enjuanes Sánchez, Luis CSIC ORCID ; Haagmans, Bart L.
Issue Date8-Aug-2018
PublisherAmerican Association for the Advancement of Science
CitationScience advances 4(8): eaas9667 (2018)
AbstractMiddle East respiratory syndrome coronavirus (MERS-CoV) continues to cause outbreaks in humans as a result of spillover events from dromedaries. In contrast to humans, MERS-CoV¿exposed dromedaries develop only very mild infections and exceptionally potent virus-neutralizing antibody responses. These strong antibody responses may be caused by affinity maturation as a result of repeated exposure to the virus or by the fact that dromedaries¿ apart from conventional antibodies¿have relatively unique, heavy chain¿only antibodies (HCAbs).
Publisher version (URL)http://dx.doi.org/10.1126/sciadv.aas9667
URIhttp://hdl.handle.net/10261/204109
DOI10.1126/sciadv.aas9667
Identifiersdoi: 10.1126/sciadv.aas9667
e-issn: 2375-2548
pmid: 30101189
Appears in Collections:(CNB) Artículos
(VICYT) Colección Especial COVID-19




Files in This Item:
File Description SizeFormat
722163.pdf1,22 MBUnknownView/Open
Show full item record
Review this work

PubMed Central
Citations

40
checked on May 24, 2022

SCOPUSTM   
Citations

50
checked on May 28, 2022

WEB OF SCIENCETM
Citations

43
checked on May 24, 2022

Page view(s)

163
checked on May 28, 2022

Download(s)

115
checked on May 28, 2022

Google ScholarTM

Check

Altmetric

Dimensions


Related articles:


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.