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Bacteriophage origin people biomarker for mastitis producing Streptococcus spp. identification and characterization by LC-ESI-MS/MS

AuthorsAbril, A. G.; Carrera, Mónica ; Böhme, K.; Barros-Velázquez, J. ; Rama, J. L. R.; Sieiro, C.; Villa, T. G.; Calo-Mata, Pilar
KeywordsStreptococcus detection
Mass spectrometry
Phage peptide biomarker
Issue Date2019
Citation4th Meeting of Medicinal Biotechnology (2019)
AbstractStreptococcus includes numerous mastitis causing species, being responsible for high economic losses as well as human health issues Recently, new rapid molecular microbial diagnostic methods based on genomics and proteomics have been developed in order to achieve faster and more effectively species identification than classical and culture based methods which are labour intensive Liquid chromatography electrospray ionization tandem mass spectrometry (LC ESI MS/MS) has been used for the analysis of bacterial pathogen strain specific diagnostic peptides 1 2 As bacteriophages are high specific to their host pathogens, their nucleic acids, antibodies, phage display peptides ( and most recently phage’s receptor binding proteins ( have been studied as biosensor for pathogen detection 3 4 In addition, LC ESI MS/MS techniques have been employed for the identification and detection of bacterial bacteriophages 5 However, any study has been published for Streptococcus phage detection and identification by LC MS MS so far
DescriptionPoster.-- 4th Meeting of Medicinal Biotechnology, Porto, May 17th 2019
Appears in Collections:(IIM) Comunicaciones congresos
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