Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/201623
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dc.contributor.authorGenebat, Migueles_ES
dc.contributor.authorTarancón-Díez, Lauraes_ES
dc.contributor.authorPulido, Ildefonsoes_ES
dc.contributor.authorÁlvarez-Ríos, Ana Isabeles_ES
dc.contributor.authorMuñoz-Fernandez, M. Angeleses_ES
dc.contributor.authorRuiz-Mateos, Ezequieles_ES
dc.contributor.authorLeal, Manueles_ES
dc.date.accessioned2020-02-24T08:44:28Z-
dc.date.available2020-02-24T08:44:28Z-
dc.date.issued2019-09-
dc.identifier.citationAntiviral Research 169: 104527 (2019)es_ES
dc.identifier.issn0166-3542-
dc.identifier.urihttp://hdl.handle.net/10261/201623-
dc.description.abstract[Objectives] to analyze the association between HCV coinfection and cumulative infections with the development of a cardiovascular disease in HIV-infected subjects.es_ES
dc.description.abstract[Methods] HIV-infected subjects attended at Virgen del Rocio University Hospital, between January 1982 and March 2018, were considered if fulfilled the following criteria: at least two visits to the HIV clinic, clinical records with data about VZV reactivation and bacterial infections, available data on HCV coinfection status. Atherogenic cardiovascular events were registered. To analyze factors associated with the development of cardiovascular event, a logistic regression analysis was performed.es_ES
dc.description.abstract[Results] 823 subjects were included in the study. During the observational period, 58/823 (7.05%) developed a cardiovascular event. Advanced age at HIV-1 diagnosis, a low T-CD4 nadir, HCV coinfection and the burden of infections were independently associated with the risk of developing a cardiovascular event, apart from lipid levels and diabetes.es_ES
dc.description.abstract[Conclusions] both HCV and the burden of infections are associated with an increased risk of cardivascular event in HIV-infected patients, together with other cardiovascular risk factors. Therapeutic strategies such as HCV erradication or VZV immunization could ameliorate cardiovascular risk in these subjects.es_ES
dc.language.isoenges_ES
dc.publisherElsevieres_ES
dc.rightsclosedAccesses_ES
dc.subjectInfectiones_ES
dc.subjectAtherosclerosises_ES
dc.subjectHepatitis Ces_ES
dc.subjectHIVes_ES
dc.titleHepatitis C virus and cumulative infections are associated with atherogenic cardiovascular events in HIV-infected subjectses_ES
dc.typeartículoes_ES
dc.identifier.doi10.1016/j.antiviral.2019.05.016-
dc.description.peerreviewedPeer reviewedes_ES
dc.relation.publisherversionhttps://doi.org/10.1016/j.antiviral.2019.05.016es_ES
dc.relation.csices_ES
oprm.item.hasRevisionno ko 0 false*
item.fulltextNo Fulltext-
item.openairetypeartículo-
item.cerifentitytypePublications-
item.languageiso639-1en-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
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