English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/200637
Share/Impact:
Statistics
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:

Title

Label-free plasmonic biosensors for point-of-care diagnostics: a review

AuthorsSoler, María ; Huertas, César S.; Lechuga, Laura M.
KeywordsNanoplasmonic biosensors
Point of care diagnostics
Clinical applications
Lab-on-a-chip integration
Portable devices
Issue Date2019
PublisherTaylor & Francis
CitationExpert Review of Molecular Diagnostics 19(1): 71-81 (2019)
Abstract[Introduction]: Optical biosensors, particularly those based on nanoplasmonics technology, have emerged in recent decades as a potential solution for disease diagnostics and therapy follow-up at the point-of-care (POC). These biosensor platforms could overcome some of the challenges faced in conventional diagnosis techniques offering label-free assays with immediate results and employing small and user-friendly devices.
[Areas covered]: In this review, we will provide a critical overview of the recent advances in the development of nanoplasmonic biosensors for the POC diagnostics. We focus on those systems with demonstrated capabilities for integration in portable platforms, highlighting some of the most relevant diagnostics applications targeting proteins, nucleic acids, and cells as disease biomarkers.
[Expert commentary]: Despite the attractive features of label-free nanoplasmonic sensors in terms of miniaturization and analytical robustness, the route toward an effective clinical implementation involves the integration of fully automated microfluidic systems for sample processing and analysis, and the optimization of surface biofunctionalization procedures. Additionally, the development of multiplexed sensors for high-throughput analysis and including specific neoantigens and novel biomarkers in detection panels will provide the means for delivering a powerful analytical technology for an accurate and improved medical diagnosis.
Publisher version (URL)https://doi.org/10.1080/14737159.2019.1554435
URIhttp://hdl.handle.net/10261/200637
DOI10.1080/14737159.2019.1554435
ISSN1473-7159
E-ISSN1744-8352
Appears in Collections:(CIN2) Artículos
Files in This Item:
File Description SizeFormat 
laberevie.pdf1,06 MBAdobe PDFThumbnail
View/Open
Show full item record
Review this work
 

Related articles:


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.