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Título

Gut Microbiota and Probiotics in Modulation of Epithelium and Gut-Associated Lymphoid Tissue Function

AutorSanz, Yolanda; Palma, Giada de
Palabras claveGut microbiota
Probiotics
Mucosal immunity
Regulatory T cells
Fecha de publicacióndic-2009
EditorTaylor & Francis
CitaciónInternational Reviews of Immunology 28 (6): 397-413 (2009)
ResumenThe intestinal tract mucosa is exposed to a vast number of environmental antigens and a large community of commensal bacteria. The mucosal immune system has to provide both protection against pathogens and tolerance to harmless bacteria. Immune homeostasis depends on the interaction of indigenous commensal and transient bacteria (probiotics) with various components of the epithelium and the gut-associated lymphoid tissue. Herein, an update is given of the mechanisms by which the gut microbiota and probiotics are translocated through the epithelium, sensed via pattern-recognition receptors, and activate innate and adaptive immune responses.
Descripción17 pages, 2 figures.
Versión del editorhttp://dx.doi.org/10.3109/08830180903215613
URIhttp://hdl.handle.net/10261/19871
DOI10.3109/08830180903215613
ISSN0883-0185
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