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http://hdl.handle.net/10261/198669
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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Castro, Javier de | es_ES |
dc.contributor.author | González-Larriba, J. L. | es_ES |
dc.contributor.author | Vázquez-Estévez, Sergio | es_ES |
dc.contributor.author | Massutí, Bartomeu | es_ES |
dc.contributor.author | Sánchez-Torres, J. M. | es_ES |
dc.contributor.author | Dómine, Manuel | es_ES |
dc.contributor.author | Garrido, Pilar | es_ES |
dc.contributor.author | Calles, A. | es_ES |
dc.contributor.author | Artal, A. | es_ES |
dc.contributor.author | Collado, Rosa | es_ES |
dc.contributor.author | García, R. | es_ES |
dc.contributor.author | Sereno, M. | es_ES |
dc.contributor.author | Majem, M. | es_ES |
dc.contributor.author | Macías, J. A. | es_ES |
dc.contributor.author | Juan-Vidal, Óscar | es_ES |
dc.contributor.author | Gómez-Codina, J. | es_ES |
dc.contributor.author | Hernández, B. | es_ES |
dc.contributor.author | Lázaro, M. | es_ES |
dc.contributor.author | Ortega, A. L. | es_ES |
dc.contributor.author | Cobo, M. | es_ES |
dc.contributor.author | Trigo, José Manuel | es_ES |
dc.contributor.author | Carcereny Costa, Enric | es_ES |
dc.contributor.author | Rolfo, C. | es_ES |
dc.contributor.author | Maciá, S. | es_ES |
dc.contributor.author | Muñoz, J. | es_ES |
dc.contributor.author | Diz, Paula | es_ES |
dc.contributor.author | Méndez, M. | es_ES |
dc.contributor.author | Rosillo, F. | es_ES |
dc.contributor.author | Paz-Ares, Luis | es_ES |
dc.contributor.author | Cardona, J. V. | es_ES |
dc.contributor.author | Isla, María Dolores | es_ES |
dc.date.accessioned | 2020-01-22T13:33:18Z | - |
dc.date.available | 2020-01-22T13:33:18Z | - |
dc.date.issued | 2017-02 | - |
dc.identifier | doi: 10.1007/s12094-016-1527-8 | - |
dc.identifier | issn: 1699-048X | - |
dc.identifier | e-issn: 1699-3055 | - |
dc.identifier.citation | Clinical and Translational Oncology 19(2): 219-226 (2017) | es_ES |
dc.identifier.uri | http://hdl.handle.net/10261/198669 | - |
dc.description.abstract | [Background/Aim] First-line bevacizumab-based therapies have been shown to improve clinical outcomes in patients with non-squamous non-small-cell lung cancer (NSCLC). We aimed to descriptively analyse patients with non-squamous NSCLC who received a long-term period of maintenance bevacizumab. | - |
dc.description.abstract | [Patients and methods] This retrospective study included 104 patients who had already reached a progression-free survival (PFS) of at least 9 months. | - |
dc.description.abstract | [Results] Median overall survival and PFS were 30.7 and 15.1 months, respectively. The overall response rate was 83 %. Weight loss ≤5 %, ECOG PS = 0, or low number of metastatic sites seem to be predictive factors of good evolution. The incidence of bevacizumab-related adverse events appeared to be similar as the previous studies. | - |
dc.description.abstract | [Conclusion] Our findings show that there is a long-term survivor group whom the administration of bevacizumab resulted in a relevant prolongation of response without new safety signals. Due to the population heterogeneity, it was not possible to identify the standardised predictive factors. | - |
dc.description.sponsorship | This work was supported by Roche Farma, S.A., Spain. | - |
dc.language | eng | - |
dc.publisher | Springer Nature | es_ES |
dc.rights | closedAccess | - |
dc.subject | Non-squamous NSCLC | - |
dc.subject | First-line treatment | - |
dc.subject | Bevacizumab | - |
dc.subject | Bevacizumab maintenance therapy | - |
dc.subject | Routine clinical practice setting | - |
dc.subject | Observational study | - |
dc.title | Long-term survival in advanced non-squamous NSCLC patients treated with first-line bevacizumab-based therapy | es_ES |
dc.type | artículo | es_ES |
dc.identifier.doi | 10.1007/s12094-016-1527-8 | - |
dc.relation.publisherversion | http://dx.doi.org/10.1007/s12094-016-1527-8 | - |
dc.date.updated | 2020-01-22T13:33:18Z | - |
dc.contributor.funder | Roche | - |
dc.relation.csic | Sí | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/100004337 | es_ES |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.openairetype | artículo | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | No Fulltext | - |
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