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Title

Synthesis of enantiomerically pure β,β-diphenylalanine (Dip) and fluorenylglycine (Flg)

AuthorsRoyo, Soledad; Jiménez, Ana I. CSIC ORCID; Cativiela, Carlos CSIC ORCID
Issue DateSep-2006
PublisherElsevier
CitationTetrahedron Asymmetry 17(16): 2393-2400 (2006)
AbstractA new strategy for the preparation of both enantiomers of two phenylalanine analogues, β,β-diphenylalanine and fluorenylglycine, has been developed. The combination of a high yielding racemic synthesis and a very efficient resolution procedure has provided significant amounts of each amino acid in enantiomerically pure form and suitably protected for use in peptide synthesis. This methodology can be easily applied to the preparation of larger quantities of enantiopure compounds.
Description8 pages, 6 schemes, 3 figures.
Publisher version (URL)http://dx.doi.org/10.1016/j.tetasy.2006.08.007
URIhttp://hdl.handle.net/10261/19830
DOI10.1016/j.tetasy.2006.08.007
ISSN0957-4166
Appears in Collections:(ICMA) Artículos

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