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Título

The FASTK family of proteins: emerging regulators of mitochondrial RNA biology

AutorJourdain, Alexis A.; Popow, Johannes; Fuente, Miguel A. de la CSIC ORCID; Martinou, Jean-Claude; Anderson, Paul; Simarro-Grande, María CSIC ORCID
Fecha de publicación2017
EditorOxford University Press
CitaciónNucleic Acids Research 45(19): 10941-10947 (2017)
ResumenThe FASTK family proteins have recently emerged as key post-transcriptional regulators of mitochondrial gene expression. FASTK, the founding member and its homologs FASTKD1–5 are architecturally related RNA-binding proteins, each having a different function in the regulation of mitochondrial RNA biology, from mRNA processing and maturation to ribosome assembly and translation. In this review, we outline the structure, evolution and function of these FASTK proteins and discuss the individual role that each has in mitochondrial RNA biology. In addition, we highlight the aspects of FASTK research that still require more attention.
Versión del editorhttps://doi.org/10.1093/nar/gkx772
URIhttp://hdl.handle.net/10261/197454
DOI10.1093/nar/gkx772
ISSN0305-1048
E-ISSN1362-4962
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