Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/194051
COMPARTIR / EXPORTAR:
SHARE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Título: | Effect of the long-term intake of a casein hydrolysate on mucin secretion and gene expression in the rat intestine |
Autor: | Fernández-Tomé, Samuel CSIC ORCID; Martínez-Maqueda, D. CSIC ORCID; Tabernero, María CSIC; Largo, Carlota; Recio, Isidra CSIC ORCID ; Miralles, Beatriz CSIC ORCID | Palabras clave: | Casein hydrolysates Faecal mucin Rat intestine Gene expression O-linked glycoprotein |
Fecha de publicación: | 2017 | Editor: | Elsevier | Citación: | Journal of Functional Foods 33: 176-180 (2017) | Resumen: | The aim of the present study was to investigate the in vivo effect on rat intestinal mucus production of a casein hydrolysate that had been previously shown a mucin stimulatory effect in human goblet cells (HT29-MTX). A significant rise of O-linked glycoproteins in faeces after 2 and 8 weeks of the casein hydrolysate intake was observed. In agreement with this increased secretion, the relative expression for the genes that encode the secreted MUC2 and the membrane-bound MUC3 was significantly increased in ileum and colon. Mucus material in the small intestine lumen of rats fed the casein hydrolysate was higher than that found in control rats, however the change did not reach statistical difference. This study confirms in vivo the potential effect on mucus gastrointestinal protection of this casein hydrolysate. | Versión del editor: | https://doi.org/10.1016/j.jff.2017.03.036 | URI: | http://hdl.handle.net/10261/194051 | ISSN: | 1756-4646 10.1016/j.jff.2017.03.036 |
E-ISSN: | 2214-9414 |
Aparece en las colecciones: | (CIAL) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
accesoRestringido.pdf | 59,24 kB | Adobe PDF | Visualizar/Abrir |
CORE Recommender
Page view(s)
184
checked on 18-mar-2024
Download(s)
21
checked on 18-mar-2024
Google ScholarTM
Check
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.