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A new constrained proline analogue with an 8-azabicyclo[3.2.1]octane skeleton.

AuthorsCasabona, Diego; Jiménez, Ana I. ; Cativiela, Carlos
KeywordsConstrained amino acid
Quaternary amino acid
Proline analogue
Bbicyclic proline
Ring-closing metathesis
Issue Date4-Jun-2007
CitationTetrahedron. 63(23): 5056–5061 (2007)
AbstractA straightforward synthesis of 8-azabicyclo[3.2.1]octane-1-carboxylic acid, a new proline analogue with a bicyclic structure, is described. The procedure makes use of readily available starting materials and involves simple, high-yielding transformations.
Description2 figures, 2 schemes.
Publisher version (URL)http://dx.doi.org/10.1016/j.tet.2007.03.115
Appears in Collections:(ICMA) Artículos
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