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Synthesis of α,γ-peptide hybrids by selective conversion of glutamic acid units

AuthorsSaavedra, Carlos J.; Boto, Alicia ; Hernández, Rosendo
KeywordsPeptide hybrids
Glutamic acid units
Selective conversion
Issue Date25-Jun-2012
PublisherACS Publications
CitationOrganic Letters 14(13): 3542-3545 (2012)
AbstractThe site-selective modification of small peptides at a glutamate residue allows the ready preparation of α,γ-hybrids. In this way, a single peptide can be transformed into a variety of hybrid derivatives. The process takes place under very mild conditions, and good global yields are obtained.
Publisher version (URL)https://pubs.acs.org/doi/10.1021/ol301552c
Identifiersdoi: 10.1021/ol301552c
issn: 1523-7060
e-issn: 1523-7052
Appears in Collections:(IPNA) Artículos
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