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Anthraquinone glycosides from Cassia roxburghii and evaluation of its free radical scavenging activity

AuthorsEl-Toumy, Sayed A.; El Souda, Sahar S.; Mohamed, Tahia K.; Brouard, Ignacio ; Bermejo, Jaime
KeywordsFree radicals scavenging activity
Cassia roxburghii
Issue Date1-Oct-2012
CitationCarbohydrate Research 360: 47-51 (2012)
AbstractThe methanolic extract of the leaves of Cassia roxburghii DC., was investigated for its anthraquinone glycosides and antioxidant activity. Two new anthraquinone glycosides named emodin 1-O-β-d-glucopyranosyl-(1→2)- glucopyranoside (1) and aloemodin 8-O-β-d-glucopyranosyl-(1→6)- glucopyranoside (2) along with aloemodin 8-O-β-d-glucopyranoside (3), emodin (4), aloemodin (5) and one flavonoid, quercetin-3-O-α-l- rhamnopyranoside, were isolated from the leaves of C. roxburghii. Structures of the isolated compounds were established by UV, HRESI-MS, and 1D/2D 1H/ 13C NMR spectroscopy. The total extract and some isolated compounds were determined against DPPH (2,2-diphenyl-1-(2,4,6- trinitrophenyl)hydrazinyl radical, for their free radical scavenging activity, the total alcoholic extract showed strong antioxidant activity while the two new compounds showed weak antioxidant activity.
Publisher version (URL)https://doi.org/10.1016/j.carres.2012.07.020
Identifiersdoi: 10.1016/j.carres.2012.07.020
issn: 0008-6215
e-issn: 1873-426X
Appears in Collections:(IPNA) Artículos
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