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Is BMP4 involved in the regulation of the early stages of gametogenesis in the European seabass?

AuthorsSimón-Díaz, Marisol; Martos-Sitcha, Juan Antonio ; Mancera, Juan Miguel; Prat, Francisco
Issue Date2017
PublisherUniversidad de Vigo
CitationAdvances in comparative endocrinology: vol. IX: 164-166 (2017)
AbstractThe aim of the present work is to study the involvement of BMP4 in the control of the initial stages of gonadal development in both males and females of European seabass, Dicentrarchus labrax, in order to determinate its relevance in the control of reproduction. Sequences of bmp4 and its type-I receptor, bmpr1a, and two forms of its type-II receptor, bmpr2 and bmpr2-like, were found by blast analysis against the NCBI whole-genome shotgun contigs (wgs) database for D. labrax. All four sequences were confirmed by PCR using ovarian and testis cDNA and specific primers designed to the respective genomic sequences. Tissue specificity analysis showed expression of all four genes in almost of tissues studied, including ovary and testis. Expression of bmp4, bmpr1a, bmpr2 and bmpr2-like in ovaries and testes during the reproductive cycle indicates that BMP4 system is involved in the regulation of gametogenesis in the European sea bass.
DescriptionTrabajo presentado en el 11º Congreso de la Asociación Ibérica de Endocrinología Comparada (AIEC), celebrado en Vigo (España), del 13 al 15 de julio de 2017
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